Professor of Statistical Genetics

My research interests include, for humans, pedigree analysis, gene mapping, selection, recombination, de novo and somatic mutations, haplotype phasing, and parent of origin specific genetic effects.

One new area of research for my group is genotype-phenotype studies where genetic data on one or both parents of the proband – the phenotyped individual --- are available. Efforts include data analysis, methodology development, data acquisition, and theoretical investigations.

Publications

Tuesday, 01 August 2023
Benonisdottir, S. and Kong, A. (2023) “Studying the genetics of participation using footprints left on the ascertained genotypes.”, Nature genetics, 55(8), pp. 1413–1420.
Wednesday, 01 June 2022
Young, A. et al. (2022) “Mendelian imputation of parental genotypes improves estimates of direct genetic effects.”, Nature genetics, 54(6), pp. 897–905.
Sunday, 01 September 2019
Young, A. et al. (2019) “Deconstructing the sources of genotype-phenotype associations in humans.”, Science (New York, N.Y.), 365(6460), pp. 1396–1400.
Saturday, 01 December 2018
Jónsson, H. et al. (2018) “Multiple transmissions of de novo mutations in families.”, Nature genetics, 50(12), pp. 1674–1680.
Monday, 13 August 2018
Young, A. et al. (2018) “Relatedness disequilibrium regression estimates heritability without environmental bias”, Nature Genetics, 50(9), pp. 1304–1310.
Monday, 01 January 2018
Kong, A. et al. (2018) “The nature of nurture: Effects of parental genotypes.”, Science (New York, N.Y.), 359(6374), pp. 424–428.
Friday, 01 September 2017
Jónsson, H. et al. (2017) “Parental influence on human germline de novo mutations in 1,548 trios from Iceland.”, Nature, 549(7673), pp. 519–522.
Friday, 01 September 2017
Jónsson, H. et al. (2017) “Whole genome characterization of sequence diversity of 15,220 Icelanders.”, Scientific data, 4, p. 170115.
Tuesday, 01 August 2017
Zink, F. et al. (2017) “Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly.”, Blood, 130(6), pp. 742–752.
Sunday, 01 January 2017
Kong, A. et al. (2017) “Selection against variants in the genome associated with educational attainment.”, Proceedings of the National Academy of Sciences of the United States of America, 114(5), pp. E727 - E732.
Tuesday, 01 November 2016
Gunnarsson, B. et al. (2016) “A sequence variant associating with educational attainment also affects childhood cognition.”, Scientific reports, 6, p. 36189.
Friday, 01 January 2016
Okbay, A. et al. (2016) “ Genome-wide association study identifies 74 loci associated with educational attainment ”, Nature [Preprint].
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Augustine Kong

PhD
Professor of Statistical Genetics
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My research interests include, for humans, pedigree analysis, gene mapping, selection, recombination, de novo and somatic mutations, haplotype phasing, and parent of origin specific genetic effects.

One new area of research for my group is genotype-phenotype studies where genetic data on one or both parents of the proband – the phenotyped individual --- are available. Efforts include data analysis, methodology development, data acquisition, and theoretical investigations.

Publications

Tuesday, 01 August 2023
Benonisdottir, S. and Kong, A. (2023) “Studying the genetics of participation using footprints left on the ascertained genotypes.”, Nature genetics, 55(8), pp. 1413–1420.
Wednesday, 01 June 2022
Young, A. et al. (2022) “Mendelian imputation of parental genotypes improves estimates of direct genetic effects.”, Nature genetics, 54(6), pp. 897–905.
Sunday, 01 September 2019
Young, A. et al. (2019) “Deconstructing the sources of genotype-phenotype associations in humans.”, Science (New York, N.Y.), 365(6460), pp. 1396–1400.
Saturday, 01 December 2018
Jónsson, H. et al. (2018) “Multiple transmissions of de novo mutations in families.”, Nature genetics, 50(12), pp. 1674–1680.
Monday, 13 August 2018
Young, A. et al. (2018) “Relatedness disequilibrium regression estimates heritability without environmental bias”, Nature Genetics, 50(9), pp. 1304–1310.
Monday, 01 January 2018
Kong, A. et al. (2018) “The nature of nurture: Effects of parental genotypes.”, Science (New York, N.Y.), 359(6374), pp. 424–428.
Friday, 01 September 2017
Jónsson, H. et al. (2017) “Parental influence on human germline de novo mutations in 1,548 trios from Iceland.”, Nature, 549(7673), pp. 519–522.
Friday, 01 September 2017
Jónsson, H. et al. (2017) “Whole genome characterization of sequence diversity of 15,220 Icelanders.”, Scientific data, 4, p. 170115.
Tuesday, 01 August 2017
Zink, F. et al. (2017) “Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly.”, Blood, 130(6), pp. 742–752.
Sunday, 01 January 2017
Kong, A. et al. (2017) “Selection against variants in the genome associated with educational attainment.”, Proceedings of the National Academy of Sciences of the United States of America, 114(5), pp. E727 - E732.
Tuesday, 01 November 2016
Gunnarsson, B. et al. (2016) “A sequence variant associating with educational attainment also affects childhood cognition.”, Scientific reports, 6, p. 36189.
Friday, 01 January 2016
Okbay, A. et al. (2016) “ Genome-wide association study identifies 74 loci associated with educational attainment ”, Nature [Preprint].

Recent